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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
17.58
Human Site:
S1254
Identified Species:
29.74
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
S1254
K
K
L
A
E
S
L
S
S
D
P
E
V
L
L
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
S1254
K
K
L
A
E
S
L
S
S
D
P
E
V
L
L
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
S1253
K
K
L
A
E
S
L
S
S
D
P
E
V
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
K1253
F
N
T
A
T
L
K
K
L
A
E
S
L
S
S
Rat
Rattus norvegicus
Q6AYJ1
621
69624
D463
A
L
I
A
Q
H
F
D
E
V
W
N
A
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
G633
E
V
L
L
Q
I
D
G
V
T
E
D
K
L
E
Chicken
Gallus gallus
Q9I920
1142
126164
S984
K
K
I
A
E
T
L
S
S
D
A
E
V
L
L
Frog
Xenopus laevis
Q9DEY9
1364
152305
S1206
R
R
I
A
E
S
L
S
P
E
P
E
V
L
L
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
C1103
A
R
F
V
Q
D
N
C
E
K
V
G
N
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
P1325
K
S
M
A
E
T
L
P
I
T
E
K
D
M
C
Honey Bee
Apis mellifera
XP_396209
961
109321
D803
K
D
T
I
T
M
L
D
A
T
D
D
A
K
Q
Nematode Worm
Caenorhab. elegans
O18017
988
110641
L830
A
V
A
E
S
S
G
L
S
G
P
Y
S
I
V
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
A1229
R
G
N
N
Q
F
T
A
N
H
Y
A
D
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
E1280
N
N
L
R
M
T
Y
E
R
L
R
E
L
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
6.6
6.6
N.A.
13.3
80
66.6
0
N.A.
26.6
13.3
20
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
13.3
20
N.A.
33.3
93.3
93.3
13.3
N.A.
53.3
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
58
0
0
0
8
8
8
8
8
15
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
8
8
15
0
29
8
15
15
8
0
% D
% Glu:
8
0
0
8
43
0
0
8
15
8
22
43
0
0
8
% E
% Phe:
8
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
8
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
22
8
0
8
0
0
8
0
0
0
0
8
0
% I
% Lys:
43
29
0
0
0
0
8
8
0
8
0
8
8
8
0
% K
% Leu:
0
8
36
8
0
8
50
8
8
8
0
0
15
43
50
% L
% Met:
0
0
8
0
8
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
15
8
8
0
0
8
0
8
0
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
36
0
0
0
0
% P
% Gln:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
15
15
0
8
0
0
0
0
8
0
8
0
0
8
0
% R
% Ser:
0
8
0
0
8
36
0
36
36
0
0
8
8
15
8
% S
% Thr:
0
0
15
0
15
22
8
0
0
22
0
0
0
0
0
% T
% Val:
0
15
0
8
0
0
0
0
8
8
8
0
36
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _